AdiPearl® advances regenerative medicine for aesthetic applications. Based on Swiss research at EPFL, it represents a new paradigm in tissue regeneration.
AdiPearl® uses a polysaccharides-based, porous scaffold that invites the body's own stem cells to form young, vascularized adipose tissue.
As the scaffold is naturally resorbed, it is replaced by real, living tissue — not just temporary volume.
Injection enabling immediate volumizing effect while creating a temporary structure within the tissue.
Following implantation, the scaffold supports the deposition of extracellular matrix proteins such as collagen and elastin.
Cells migrate into the scaffold structure and progressively form young, vascularized adipose tissue while the scaffold gradually degrades.
After several months, the scaffold is fully resorbed and replaced by newly formed adipose tissue, maintaining restored volume and improved tissue quality.
AdiPearl® is based on a medical-grade, natural polysaccharide formed into a soft, sponge-like scaffold.
Micropores provide pathways for stem cells to move and connect.
The open structure supports the formation of new blood vessels.
Micropores give cells space to regenerate and build new tissue volume where needed.
The scaffold structure provides pathways that allow surrounding cells to migrate into the biomaterial, supporting early tissue formation and vascularization.
A small amount of scaffold is injected into the desired area. Its structure creates natural pathways for cells and micro-vessels to enter.
The body's own signals attract stem and progenitor cells to the site. Early vascularization is supported.
Recruited stem cells differentiate into young, vascular adipose tissue — restoring volume exactly where needed.
As the tissue matures, the scaffold gradually resorbs, leaving only real, living tissue.
AdiPearl® uses a porous, natural scaffold to guide native adipogenesis. Stem cells migrate in, blood vessels form, and new adipocytes develop. This creates a regenerative pathway — not surgery, not a filler, but a true regenerative platform.
Fat grafting is a surgical procedure that transfers fat from one part of the body to another. AdiPearl® supports the body in growing tissue exactly where it is needed, using a single injection and the body's own regenerative processes.
No. The scaffold is designed to gradually resorb as new tissue forms. Pro-regenerative macrophages guide this process, leaving behind living tissue — not foreign material.
Adipose tissue requires a blood supply to survive. The scaffold's structure supports the formation of new blood vessels, which nourish the growing tissue and enable natural integration.
AdiPearl® is investigational and not yet commercially available.
For physicians interested in pioneering this new approach, or for patients seeking to participate in clinical research.